endolracheal tube, if Jocal anesthelrcs (to paralyze this irritant receptors)

endolracheal tube, if Jocal anesthelrcs (to paralyze this irritant receptors) are not sufficiently used, bronchospasm many develop Similarly, sneezing is also due lo irritation of such receptors in the nasal mucous membrane) So, in short, lung irritant receptors are ardinanly not called into action, when Ihey operate, the rhythm of respiration is severely altered Afferent impulses from these receptors are earned by vagal (afferent) fibers V Peripheral ctomoreceplors Chemoreceptors are present in various anatomical sites of the body and they serve vanous purposes In connection with the control of respiratory1 system we have two types of chenoreceptors, (i) central chemofeceptors (described afterwards), and (ii) penphtral chetmoreceptors etanls ol penpheral chmoreciplors will be given below The following sketches may be noted at present Penpheral chemoreceptors include two sets, (a) cartid body [present at the root of eiiernaf carotid artery fig.4 3 5) and (b) aortic bodies, present in the arch of aorta. They are so placed in the vascular endothelum that they come in direct.cortfacl with the blood They can delect (= analyze) the anenal blood P02 (= Pa02)h PC02 (= Pa C02) and pH When Pa 02 is low, they are stimulated send signals lo the respiratory center respiration stmulated (hyperpnea), by which Pa 02 deficiency is corrected These chetmoreceptors can also sense (= analyze) the PaC02 and when PaCQ3 is high they are ;[stimulaied hyperpnea a correction of PaC02 values However, so far as PaC02 is concerned, central chemoreceptors (not the peripheral ch em o receptors) play the dominant role On the contrary, for Pa02. there is no central chemo receptors and.the. PaO2 correction occurs via the peripheral chemoreceptors. Low blood pH is also sensed by The