probably in the walls of the alveoli, when stimulated they produce apnea (=

, probably in the walls of the alveoli, when stimulated they produce apnea (= stoppage of respiration) followed by hyperpnea. bradyeardia and hypotension In addition. 11 can also produce bronchospasm Further, stmulation of J receptors Ie ads to the inhibition of contraction of the skeletal muscles Therefore. J reflex = stimulation of J receptor bradycardia + hypotension + hyperpnea + weakness of skeletal muscles When are these receptors stimulated? Answer is, it is slimulaied in pathological conditions like, (i) sma emboh in the pulmonary blood vessels and (ii) pulmonary edema J receptors and muscular exercise What causes the physical exhaustion and muscular fatigua during a hard exercise is not clearly known (In general, it is believed that fatigue in intact man is caused by central mechanism, ie . mechanism residing in the synapses of the central nervous system) Paintil argued that during muscular exercise. cungestion of the pulmonary capillaries lead to slight accumulation of interstitial fluid (recall, at health during rest, the pulmonary interstium is dry) this in turn Ie ads to stimulation of J receptors muscular weakness Teteologically, this may be viewed as a naturally exsting 'brake'mechanism in the body, operating to prevent excessive exercise However, paintals vews regarding the cause of muscular weakness in physical exercise is yei to be univsrsally agreed